Keywords
chronic pancreatitis, treatment, evidence-based research, pain management, substitution enzyme therapy
How to Cite
Osipenko, M. F., Bordin, D. S., & Bikbulatova, E. A. (2016). The evidence base for the use of drugs in the treatment of chronic pancreatitis. Herald of Pancreatic Club, 31(2), 17-20. https://doi.org/10.33149/vkp.2016.02.03
Abstract views: 139 PDF Downloads: 104 PDF Downloads: 126
Abstract
The present article discusses the level of evidence of different approaches to the treatment of pancreatic pain syndrome and substantiates the necessity of a rational choice of the most optimal therapy by medical preparations for relief of chronic pain in view of their possible side effects and complications.
References
1. Механизмы боли при хроническом панкреатите: что и кому назначить практикующему врачу? / Ю. А. Кучерявый, А. В. Смирнов, Р. Т. Джаватханова, Н. Н. Устинова // Фарматека. – 2013. – № 14. – С. 21–27.
2. Alcohol intake, cigarette smoking, and body mass index in patients with alcohol-associated pancreatitis / G. Talamini, B. Vaona, C. Bassi [et al.] // J. Clin. Gastroenterol. – 2000. – Vol. 31. – P. 314–317.
3. Antioxidant therapy for recurrent pancreatitis : placebo controlled trial / S. Uden, D. Bilton, L. Nathan [et al.] // Aliment. Pharmacol. Ther. – 1990. – Vol. 4. – P. 357–371.
4. Basurto Ona X. Opioids for acute pancreatitis pain / X. Basurto Ona, D. Rigau Comas, G. Urrútia // Cochrane Database Syst Rev. – 2013. – Vol. 7. –CD009179.
5. Chronic pancreatitis and its effect on employment and health care experience : results of a prospective American multicenter study / Т. Gardner, A. Kennedy, A. Gelrud [et al.] // Pancreas. – 2010. – Vol. 39. – P. 498–501.
6. Cigarette smoking accelerates progression of alcoholic chronic pancreatitis / P. Maisonneuve, A. Lowenfels, В. Muilhaupt [et al.] // Gut. – 2005. – Vol. 54. – P. 510–514.
7. Cigarette smoking as a risk factor for chronic pancreatitis : a case-control study in Japan. Research Committee on Intractable Pancreatic Diseases / Y. Lin, A. Tamakoshi, Т. Hayakawa [et al.] // Pancreas. – 2000. – Vol. 2. – P. 109–114.
8. Combined antioxidant therapy reduces pain and improves quality of life in chronic pancreatitis / G. Kirk, J. White, L. McKie [et al.] // J. Gastrointest. Surg. – 2006. – Vol. 10. – P. 499–503.
9. Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: recommendations from PancreasFest / M. R. Rickels, M. Bellin, F. G. Toledo [et al.] // Pancreatology. – 2013. – Vol. 13, No 4. – P. 336–342.
10. Dominguez-Munoz J. Pancreatic enzyme therapy for pancreatic exocrine insufficiency / J. Dominguez-Munoz // Curr. Gastroenterol. Rep. – 2007. – Vol. 9. – P. 116–122.
11. Drewes A. Diagnosis and treatment of pancreatic exocrine insufficiency / A. Drewes // World J. Gastroenterol. – 2014. – Vol. 19, No 42. – P. 7258–7266.
12. Effect of antioxidant supplementation on surrogate markes of fibrosis in chronic pancreatitis : a randomized, placebo-controlled trial / R. Dhingra, N. Singh, V. Sachdev [et al.] // Pancreas. – 2013. – Vol. 42, No 4. – P. 589–595.
13. Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis / D. Cahen, D. Gouma, Y. Nio [et al.] // N. Engl. J. Med. – 2007. – Vol. 356. – P. 676–684.
14. Grigsbi В. Antioxidants and chronic pancreatitis: theory of oxidatives stress and trials of antioxidant therapy / В. Grigsbi, H. Rodrigues-Rilo, K. Khan // Dig. Dis. Sci. – 2012. – Vol. 5, No 7. – P. 835–841.
15. Italian consensus guidelines for chronic pancreatitis / L. Frulloni, M. Massimo Falconi, A. Gabbrielli [et al.] // Dig. Liver. Dis. – 2010. – Vol. 42, Suppl. 6. – P. 381–406.
16. Kleef M. Pain in chronic pancreatitis / M. Kleef, Y. Keulemans // Pain Pract. – 2011. – Vol. 11, No 5. – P. 492–505.
17. Management of pancreatic exocrine insufficiency : Australasian Pancreatic Club recommendations / J. Toouli, A. Biankin, M. Oliver [et al.] // MJA. – 2010. – Vol. 193, No 8. – P. 461–467.
18. Opioid treatment of painful chronic pancreatitis / L. Madsen, S. Larsen [et al.] // Int. J. Pancreatol. – 2000. – Vol. 27. – P. 235–240.
19. Optimising the therapy of exocrine pancreatic insufficiency by the association of a proton pump inhibitor to enteric coated pancreatic extracts / J. Dominguez-Munoz, J. Iglesias-Garcia, M. Iglesias-Rey [et al.] // Gut. – 2006. – Vol. 55. – P. 1056–1057.
20. Pain in chronic pancreatitis / M. Puylaert, L. Kapural, J. Van Zundert [et al.] // Pain Pract. – 2011. – Vol. 11, No 5. – P. 492–505.
21. Pain in chronic pancreatitis and pancreatic cancer / К. Fasanella, В. Davis, J. Lyons [et al.] // Gastroenterol. Clin. North. Am. – 2007. – Vol. 36. – P. 335–364.
22. Paisley P. Pharmacological management of pain in chronic pancreatitis / P. Paisley, J. Kinsella // Scott. Med. J. – 2014. – Vol. 59. – P. 71.
23. A phase II trial of human secretin infusion for refractory type В pain in chronic pancreatitis / J. Levenick, C. Andrews, E. Purich [et al.] // Pancreas. –2013. – Vol. 42, No 4. – P. 596–600.
24. Physical and mental quality of life in chronic pancreatitis : a case-control study from the North American Pancreatitis Study 2 cohort / S. Amann, D. Yadav, M. Barmada [et al.] // Pancreas. – 2013. – Vol. 42. – P. 293–300.
25. A pilot study of the antioxidant effect of curcumin in tropical pancreatitis / S. Durgaprasad, C. G. Pai, Vasanthkumar [et al.] // Indian J. Med. Res. – 2005. – Vol. 122. – P. 315–318.
26. Prevalence and determinants of exocrine pancreatic insufficiency among older adults : results of a population-based study / D. Rothenbacher, M. Low, P. Hardt [et al.] // Scand. J. Gastroenterol. 2005. – Vol. 40. – P. 697–704.
27. A prospective, randomized trial comparing endoscopic and surgical therapy for chronic pancreatitis / P. Dite, M. Ruzicka, V. Zboril, I. Novotny // Endoscopy. – 2003. – Vol. 35. – P. 553–558.
28. Randomised clinical trial : pregabalin attenuates experimental visceral pain through sub-cortical mechanisms in patients with painful chronic pancreatitis / S. Olesen, C. Graversen, A. Olesen [et al.] // Aliment. Pharmacol. Ther. – 2011. – Vol. 34, No 8. – P. 878–887.
29. Randomised Clinical Trials: the efficacy and safety of pancreatin enteric-caoted minimicrospheres (Creon 40000MMS in patient with pancreatic exocrine insufficiency due to chronic pancreatitis – a double blind placebo controlled study / V. Throat, N. Reddy, S. Bhatia [et al.] // Aliment. Pharmacol. Ther. – 2012. – Vol. 36, No 5. – P. 426–436.
30. Severe chronic pancreatitis and severe liver cirrhosis have different frequencies and are independent risk factors in male Japanese alcoholics / Y. Nakamura, Y. Kobayashi, A. Ishikawa [et al.] // J. Gastroenterol. – 2004. – Vol. 39. – P. 879–887.
31. Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis : a prospective cohort study / D. Mullady, D. Yadav, S. Amann [et al.] // Gut. – 2011. – Vol. 60. – P. 77–84.
32. Use of antioxidants to treat pain in chronic pancreatitis / G. De las Heras Castano, A. Garcia de la Paz, M. Fernandez [et al.] // Rev. Esp. Enferm. Dig. – 2000. – Vol. 92. – P. 375–385.
2. Alcohol intake, cigarette smoking, and body mass index in patients with alcohol-associated pancreatitis / G. Talamini, B. Vaona, C. Bassi [et al.] // J. Clin. Gastroenterol. – 2000. – Vol. 31. – P. 314–317.
3. Antioxidant therapy for recurrent pancreatitis : placebo controlled trial / S. Uden, D. Bilton, L. Nathan [et al.] // Aliment. Pharmacol. Ther. – 1990. – Vol. 4. – P. 357–371.
4. Basurto Ona X. Opioids for acute pancreatitis pain / X. Basurto Ona, D. Rigau Comas, G. Urrútia // Cochrane Database Syst Rev. – 2013. – Vol. 7. –CD009179.
5. Chronic pancreatitis and its effect on employment and health care experience : results of a prospective American multicenter study / Т. Gardner, A. Kennedy, A. Gelrud [et al.] // Pancreas. – 2010. – Vol. 39. – P. 498–501.
6. Cigarette smoking accelerates progression of alcoholic chronic pancreatitis / P. Maisonneuve, A. Lowenfels, В. Muilhaupt [et al.] // Gut. – 2005. – Vol. 54. – P. 510–514.
7. Cigarette smoking as a risk factor for chronic pancreatitis : a case-control study in Japan. Research Committee on Intractable Pancreatic Diseases / Y. Lin, A. Tamakoshi, Т. Hayakawa [et al.] // Pancreas. – 2000. – Vol. 2. – P. 109–114.
8. Combined antioxidant therapy reduces pain and improves quality of life in chronic pancreatitis / G. Kirk, J. White, L. McKie [et al.] // J. Gastrointest. Surg. – 2006. – Vol. 10. – P. 499–503.
9. Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: recommendations from PancreasFest / M. R. Rickels, M. Bellin, F. G. Toledo [et al.] // Pancreatology. – 2013. – Vol. 13, No 4. – P. 336–342.
10. Dominguez-Munoz J. Pancreatic enzyme therapy for pancreatic exocrine insufficiency / J. Dominguez-Munoz // Curr. Gastroenterol. Rep. – 2007. – Vol. 9. – P. 116–122.
11. Drewes A. Diagnosis and treatment of pancreatic exocrine insufficiency / A. Drewes // World J. Gastroenterol. – 2014. – Vol. 19, No 42. – P. 7258–7266.
12. Effect of antioxidant supplementation on surrogate markes of fibrosis in chronic pancreatitis : a randomized, placebo-controlled trial / R. Dhingra, N. Singh, V. Sachdev [et al.] // Pancreas. – 2013. – Vol. 42, No 4. – P. 589–595.
13. Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis / D. Cahen, D. Gouma, Y. Nio [et al.] // N. Engl. J. Med. – 2007. – Vol. 356. – P. 676–684.
14. Grigsbi В. Antioxidants and chronic pancreatitis: theory of oxidatives stress and trials of antioxidant therapy / В. Grigsbi, H. Rodrigues-Rilo, K. Khan // Dig. Dis. Sci. – 2012. – Vol. 5, No 7. – P. 835–841.
15. Italian consensus guidelines for chronic pancreatitis / L. Frulloni, M. Massimo Falconi, A. Gabbrielli [et al.] // Dig. Liver. Dis. – 2010. – Vol. 42, Suppl. 6. – P. 381–406.
16. Kleef M. Pain in chronic pancreatitis / M. Kleef, Y. Keulemans // Pain Pract. – 2011. – Vol. 11, No 5. – P. 492–505.
17. Management of pancreatic exocrine insufficiency : Australasian Pancreatic Club recommendations / J. Toouli, A. Biankin, M. Oliver [et al.] // MJA. – 2010. – Vol. 193, No 8. – P. 461–467.
18. Opioid treatment of painful chronic pancreatitis / L. Madsen, S. Larsen [et al.] // Int. J. Pancreatol. – 2000. – Vol. 27. – P. 235–240.
19. Optimising the therapy of exocrine pancreatic insufficiency by the association of a proton pump inhibitor to enteric coated pancreatic extracts / J. Dominguez-Munoz, J. Iglesias-Garcia, M. Iglesias-Rey [et al.] // Gut. – 2006. – Vol. 55. – P. 1056–1057.
20. Pain in chronic pancreatitis / M. Puylaert, L. Kapural, J. Van Zundert [et al.] // Pain Pract. – 2011. – Vol. 11, No 5. – P. 492–505.
21. Pain in chronic pancreatitis and pancreatic cancer / К. Fasanella, В. Davis, J. Lyons [et al.] // Gastroenterol. Clin. North. Am. – 2007. – Vol. 36. – P. 335–364.
22. Paisley P. Pharmacological management of pain in chronic pancreatitis / P. Paisley, J. Kinsella // Scott. Med. J. – 2014. – Vol. 59. – P. 71.
23. A phase II trial of human secretin infusion for refractory type В pain in chronic pancreatitis / J. Levenick, C. Andrews, E. Purich [et al.] // Pancreas. –2013. – Vol. 42, No 4. – P. 596–600.
24. Physical and mental quality of life in chronic pancreatitis : a case-control study from the North American Pancreatitis Study 2 cohort / S. Amann, D. Yadav, M. Barmada [et al.] // Pancreas. – 2013. – Vol. 42. – P. 293–300.
25. A pilot study of the antioxidant effect of curcumin in tropical pancreatitis / S. Durgaprasad, C. G. Pai, Vasanthkumar [et al.] // Indian J. Med. Res. – 2005. – Vol. 122. – P. 315–318.
26. Prevalence and determinants of exocrine pancreatic insufficiency among older adults : results of a population-based study / D. Rothenbacher, M. Low, P. Hardt [et al.] // Scand. J. Gastroenterol. 2005. – Vol. 40. – P. 697–704.
27. A prospective, randomized trial comparing endoscopic and surgical therapy for chronic pancreatitis / P. Dite, M. Ruzicka, V. Zboril, I. Novotny // Endoscopy. – 2003. – Vol. 35. – P. 553–558.
28. Randomised clinical trial : pregabalin attenuates experimental visceral pain through sub-cortical mechanisms in patients with painful chronic pancreatitis / S. Olesen, C. Graversen, A. Olesen [et al.] // Aliment. Pharmacol. Ther. – 2011. – Vol. 34, No 8. – P. 878–887.
29. Randomised Clinical Trials: the efficacy and safety of pancreatin enteric-caoted minimicrospheres (Creon 40000MMS in patient with pancreatic exocrine insufficiency due to chronic pancreatitis – a double blind placebo controlled study / V. Throat, N. Reddy, S. Bhatia [et al.] // Aliment. Pharmacol. Ther. – 2012. – Vol. 36, No 5. – P. 426–436.
30. Severe chronic pancreatitis and severe liver cirrhosis have different frequencies and are independent risk factors in male Japanese alcoholics / Y. Nakamura, Y. Kobayashi, A. Ishikawa [et al.] // J. Gastroenterol. – 2004. – Vol. 39. – P. 879–887.
31. Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis : a prospective cohort study / D. Mullady, D. Yadav, S. Amann [et al.] // Gut. – 2011. – Vol. 60. – P. 77–84.
32. Use of antioxidants to treat pain in chronic pancreatitis / G. De las Heras Castano, A. Garcia de la Paz, M. Fernandez [et al.] // Rev. Esp. Enferm. Dig. – 2000. – Vol. 92. – P. 375–385.