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Abstract
The article presents the results of own research. The study involved 128 patients with chronic pancreatitis in the combination with non-obstructive (simple) chronic bronchitis. The control group consisted of 30 individuals who were generally healthy.
All patients were divided into two groups depending on the treatment used: the main group (64) and the comparison group (64). Patients in the comparison group received treatment according to standardised protocols. In addition to this treatment, patients in the main group were prescribed magnesium preparation and Bacillus clausii spores. The benefits of treatment in the main group were manifested in the effect on pain and dyspeptic syndromes. The inclusion of magnesium in therapy contributed to a significant reduction in uroamylase levels and endogenous pancreatin induction coefficients after a meal, restoring the correct balance between them. According to the results of a direct probe study of the exocrine function of the pancreas, it was found that the volume of duodenal contents, hourly output of trypsin, and lipase after treatment were significantly higher in the main group than in the comparison group.
During therapy involving magnesium preparation, according to sonography and ultrasound histography data, the frequency of expansion of the duct of Wirsung decreased; under the influence of both treatment options, the homogeneity of the tissue and the histographic coefficient increased significantly.
Under the influence of treatment, the dynamics of magnesium levels in the blood were not reliable. The magnesium content in the hair of patients in the main group increased significantly, while in the comparison group, there was only an insignificant tendency for this indicator to increase.
After the main treatment option, small intestinal bacterial overgrowth syndrome persisted in only 26.6% of cases in the main group and 45.3% of cases in the comparison group, according to hydrogen breath test data.
Treatment with magnesium resulted in significantly better quality of life (both physical and mental health) than in the control group.
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